Effect of Rabbit Anti-Human Liver Cathepsin

Elevated myeloid: plasmacytoid dendritic cell ratio associates with late, however not early, liver rejection in youngsters induced with rabbit antihuman thymocyte globulin.

BACKGROUND
Dendritic cells (DC) play an vital function within the induction and regulation of immune responses.
METHODS
Myeloid CD11c+ DC (MDC), which can have inflammatory capabilities, and plasmacytoid CD123+ DC (PDC), which can have tolerogenic potential, had been measured by move cytometric evaluation, cross-sectionally, as soon as, in 48 youngsters, and longitudinally (pretransplant and at days 1-60, 61-200, and 201-400 posttransplant) in 30 youngsters after liver transplantation (LTx).
All youngsters acquired cadaveric (n=53) or stay donor (n=25) liver allografts with rabbit anti-human thymocyte globulin induction and steroid-free tacrolimus remedy.
Rejectors in each teams had been these youngsters (n=35), who skilled biopsy-proven acute mobile rejection (ACR) inside 60 days of DC monitoring.

Rabbit Anti-Human Liver Cathepsin D IgG

RESULTS
Amongst rejectors within the longitudinal and cross-sectional cohorts, the MDC:PDC ratio was larger and was related to decreased PDC frequencies. Logistic regression evaluation, leave-one-out cross-validation, and receiver working attribute evaluation utilized to 30 cross-sectional topics revealed that an MDC:PDC ratio greater than or equal to 1.78 was related to rejector standing with sensitivity and specificity of 76.9% and 88.2%, respectively.
Sensitivity and specificity had been replicated within the 18 remaining cross-sectional topics (88.8% and 78.8%, respectively), however not in longitudinally monitored topics, throughout the early 60-day interval after LTx (30.76% and 62.50%, respectively). A big destructive correlation was noticed between tacrolimus entire blood concentrations and PDC frequencies (Spearman r=-0.370, P=0.005) in 48 cross-sectional topics in whom DC subsets had been monitored 1 to three years after LTx, however not throughout the early post-LTx interval.

Goat Anti-Human Apolipoprotein A-IV A(ApoA4) peptid IgG, aff pure

CONCLUSIONS
We conclude that an elevated MDC:PDC ratio associates with liver graft rejection, which happens after first 12 months in youngsters induced with rabbit anti-human thymocyte globulin.

5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]

A-1014
  • EUR 721.20
  • EUR 82.50
  • EUR 239.80
  • EUR 456.50
  • 100 µg
  • 10 ug
  • 50 ug
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5-Hydroxymethylcytosine (5-hmC) Monoclonal Antibody [HMC/4D9]

A-1018
  • EUR 702.06
  • EUR 82.50
  • EUR 239.80
  • EUR 443.30
  • 100 µg
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PRDM4 Polyclonal Antibody

A-2004
  • EUR 754.26
  • EUR 117.70
  • EUR 284.90
  • EUR 470.80
  • 100 µg
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PRDM5 Polyclonal Antibody

A-2005
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PRDM10 Polyclonal Antibody

A-2010
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PRDM11 Polyclonal Antibody

A-2011
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PRDM13 Polyclonal Antibody

A-2013
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PRDM16 Polyclonal Antibody

A-2016
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PRDM17 Polyclonal Antibody

A-2017
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EZH1 Polyclonal Antibody

A-2018
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HSF1 Polyclonal Antibody

A-2401
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PRMT3 Polyclonal Antibody

A-3003
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SET1 Polyclonal Antibody

A-3011
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SET07 Polyclonal Antibody

A-3013
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LSD1 Polyclonal Antibody

A-3018
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HDAC10 Polyclonal Antibody

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PCAF Polyclonal Antibody

A-4012
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Histone H3K9ac (Acetyl H3K9) Polyclonal Antibody

A-4022
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Histone H3K14ac (Acetyl H3K14) Polyclonal Antibody

A-4023
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Histone H3K18ac (Acetyl H3K18) Polyclonal Antibody

A-4024
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Histone H3K23ac (Acetyl H3K23) Polyclonal Antibody

A-4025
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Histone H3K56ac (Acetyl H3K56) Polyclonal Antibody

A-4026
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Histone H3K4me1 (H3K4 Monomethyl) Polyclonal Antibody

A-4031
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Histone H3K4me2 (H3K4 Dimethyl) Polyclonal Antibody

A-4032
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Histone H3K4me3 (H3K4 Trimethyl) Polyclonal Antibody

A-4033
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Histone H3K9me1 (H3K9 Monomethyl) Polyclonal Antibody

A-4034
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Histone H3K9me2 (H3K9 Dimethyl) Polyclonal Antibody

A-4035
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Histone H3K9me3 (H3K9 Trimethyl) Polyclonal Antibody

A-4036
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Histone H3K27me1 (H3K27 Monomethyl) Polyclonal Antibody

A-4037
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Histone H3K27me2 (H3K27 Dimethyl) Polyclonal Antibody

A-4038
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Histone H3K27me3 (H3K27 Trimethyl) Polyclonal Antibody

A-4039
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Histone H3K36me1 (H3K36 Monomethyl) Polyclonal Antibody

A-4040
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Histone H3K36me2 (H3K36 Dimethyl) Polyclonal Antibody

A-4041
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Histone H3K36me3 (H3K36 Trimethyl) Polyclonal Antibody

A-4042
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Histone H3K79me1 (H3K79 Monomethyl) Polyclonal Antibody

A-4043
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Histone H3K79me2 (H3K79 Dimethyl) Polyclonal Antibody

A-4044
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Histone H3K79me3 (H3K79 Trimethyl) Polyclonal Antibody

A-4045
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Histone H4K20me1 (H4K20 Monomethyl) Polyclonal Antibody

A-4046
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Histone H4K20me2 (H4K20 Dimethyl) Polyclonal Antibody

A-4047
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Histone H4K20me3 (H4K20 Trimethyl) Polyclonal Antibody

A-4048
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Histone H3K27ac (Acetyl H3K27) Polyclonal Antibody

A-4708
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CRISPR Cas9 Monoclonal Antibody [7A9]

A-9000
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CRISPR/Cas9 (SaCas9) Monoclonal Antibody [6H4]

A-9001
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CLIMP-63 Polyclonal Antibody

A-0701
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DNMT3A Polyclonal Antibody

A-1003
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DNMT3B Polyclonal Antibody

A-1004
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DNMT3L Polyclonal Antibody

A-1005
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MBD3 Polyclonal Antibody

A-1008
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MGMT Polyclonal Antibody

A-1010
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MeCP2 Polyclonal Antibody

A-1012
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TET1 Polyclonal Antibody

A-1020
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DNMT1 Polyclonal Antibody

A-1700
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TET2 Polyclonal Antibody

A-1701
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MBD2 Polyclonal Antibody

A-1713
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PRDM2 Polyclonal Antibody

A-2002
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PRDM3 Polyclonal Antibody

A-2003
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PRDM6 Polyclonal Antibody

A-2006
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PRDM12 Polyclonal Antibody

A-2012
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PRDM14 Polyclonal Antibody

A-2014
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EZH2 Polyclonal Antibody

A-2019
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Anti-peptide immunoglobulins from rabbit and hen eggs recognise recombinant human dihydroorotate dehydrogenase and a 44-kDa protein from rat liver mitochondria.

 

  • Mitochondrially certain dihydroorotate dehydrogenase catalyses the fourth sequential step within the de novo synthesis of uridine monophosphate. 312-bp and 983-bp areas of the human dihydroorotate dehydrogenase sequence (1496 bp) had been amplified by the polymerase chain response, and subcloned into the expression vector pQE 32. The id of the PCR merchandise was verified by dideoxynucleotide sequencing.

Anti-Cleaved-Cathepsin A 32ok (R326) antibody

  • Transformation of Escherichia coli pressure M15 resulted in expression of 13-kDa and 36-kDa proteins with an affinity tag consisting of six consecutive histidine residues; these proteins could possibly be purified by solubilisation in Eight M urea and by chromatography on a Ni2+-chelating resin.

 

  • In immunoblotting analyses, the fusion proteins had been recognised by polyclonal avian and mammalian anti-peptide immunoglobulins.

 

  • These had been generated in opposition to artificial peptides corresponding to 2 amino acid sequences deduced from human and rat cDNA of dihydroorotate dehydrogenase. The peptides had been synthesized as a number of copies on a branching lysyl matrix.

Human Varicella zoster virus IgM,VZV IgM ELISA Kit

201-12-1741 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Varicella zoster virus IgG,VZV-IgG ELISA Kit

201-12-1758 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Varicella zoster virus IgM(VZV IgM)ELISA Kit

GA-E1757HM-48T 48T
EUR 346.8

Human Varicella zoster virus IgM(VZV IgM)ELISA Kit

GA-E1757HM-96T 96T
EUR 559.2

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EUR 346.8

Human Varicella zoster virus IgG(VZV-IgG)ELISA Kit

GA-E1774HM-96T 96T
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Human Varicella zoster virus IgM(VZV IgM)ELISA Kit

QY-E01464 96T
EUR 433.2

Human Varicella zoster virus IgG(VZV-IgG)ELISA Kit

QY-E01465 96T
EUR 433.2

NATtrol Varicella Zoster Virus (VZV) Strain: Ellen (100 cp/mL) (1 mL)

NATVZV-0001 100 cp/mL 1 mL
EUR 103.68
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NATtrol Varicella Zoster Virus (VZV) Strain: Ellen (50,000 cp/mL) (1 mL)

NATVZV-0005 50,000 cp/mL 1 mL
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Human VZV (Varicella zoster virus) IgG ELISA Kit (Direct EIA)

EK7103 96wells/kit, with removable strips.
EUR 573.6

Human VZV (Varicella zoster virus) IgM ELISA Kit (Direct EIA)

EK7104 96wells/kit, with removable strips.
EUR 573.6

ELISA kit for Human Varicella zoster virus IgA (VZV-IgA)

KTE62708-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Human Varicella zoster virus IgA (VZV-IgA) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Varicella zoster virus IgA (VZV-IgA)

KTE62708-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Human Varicella zoster virus IgA (VZV-IgA) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Varicella zoster virus IgA (VZV-IgA)

KTE62708-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Human Varicella zoster virus IgA (VZV-IgA) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Varicella zoster virus IgM (VZV-IgM)

KTE62884-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Human Varicella zoster virus IgM (VZV-IgM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Varicella zoster virus IgM (VZV-IgM)

KTE62884-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Human Varicella zoster virus IgM (VZV-IgM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Varicella zoster virus IgM (VZV-IgM)

KTE62884-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Human Varicella zoster virus IgM (VZV-IgM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Recombinant Varicella Zoster Virus VZV gE Protein, GST, E.coli-100ug

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EUR 261.6

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EUR 448.8

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QY-E11910 96T
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Varicella Zoster Virus (VZV/chickenpox) antigens/proteins (Ellen/HF cells)

VZV16-N-500 250 ul
EUR 489.6

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EUR 578.4

Recombinant Varicella Zoster Virus gE 

7-07528 100µg Ask for price

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7-07529 500µg Ask for price

Recombinant Varicella Zoster Virus gE 

7-07530 1000µg Ask for price
  • Rabbits and laying hens had been immunized with these peptides with out conjugation to a service protein.

 

  • Comparability of the anti-peptide immunoglobulins produced from egg yolk and rabbit serum demonstrated that avian anti-(dihydroorotate dehydrogenase) immunoglobulins could also be thought of a superior various to the mammalian equal; antibodies from each sources had been relevant for all immunochemical functions.

Rabbit Anti-Human Apolipoprotein A-I protein IgG, aff pure

  • Right here, these antibodies had been utilized for identification of a 44-kDa protein from rat liver mitochondria, which was correlated with dihydroorotate dehydrogenase exercise.

 

  • A number of measurements of lymphocyte subsets in 91 youngsters handled with steroid-free tacrolimus, and rabbit anti-human thymocyte globulin induction display early reconstitution of T-cytotoxic cells, and gradual reconstitution of all different subsets, which is full after one yr.

Human Cathepsin A (CTSA) ELISA Equipment

  • Rejection-prone youngsters display considerably larger counts of lymphocytes and all subsets previous to liver transplantation, and should exemplify one foundation for enhanced baseline immunocompetence.