Top Breast Panel Multi-Tumor control slides

Multipanel immunofluorescence evaluation of tumor infiltrating lymphocytes in triple adverse breast most cancers: Evolution of tumor immune profiles and affected person prognosis.

 

  • The evolutionary adjustments in immune profiles of triple adverse breast most cancers (TNBC) aren’t properly understood, though it’s identified that immune checkpoint inhibitors have diminished exercise in closely pre-treated TNBC sufferers. This examine was designed to characterize immune profile adjustments of longitudinal tumor specimens by learning immune subsets of tumor infiltrating lymphocytes (TILs) in paired main and metastatic TNBC in a cohort of “poor end result” (relapsed inside 5 years) sufferers.

 

  • Immune profiles of TNBCs in a cohort of “good end result” (no relapse inside 5 years) sufferers have been additionally analyzed. Immune subsets have been characterised for CD4, CD8, FOXP3, CD20, CD33, and PD1 utilizing immuno-fluorescence staining in stroma, tumor, and mixed stroma and tumor tissue. TIL subsets in “good end result” versus “poor end result” sufferers have been additionally analyzed. In contrast with main, metastatic TNBCs had considerably decrease TILs by hematoxylin and eosin (H&E) staining.

HAV HAV P2C recombinant antigen

  • Stromal TILs (sTILs), however not tumoral TILs (tTILs) had considerably lowered cytotoxic CD8+ T cells (CTLs), PD1+ CTLs, and whole PD1+ TILs in metastatic in contrast with matched main TNBCs. Greater PD1+ CTLs, PD1+CD4+ helper T cells (PD1+TCONV) and all PD1+ T cells in sTILs, tTILs and whole stromal and tumor TILS (s+tTIL) have been all related to higher prognosis.

 

  • In abstract, TIL subsets lower considerably in metastatic TNBCs in contrast with matched main. Hellogher PD1+ TILs are related to higher prognosis in early stage TNBCs. This discovering helps the appliance of immune checkpoint inhibitors early within the remedy of TNBCs

Tetranectin (CLEC3B) Antibody

Breast Panel Multi-Tumor control slides

TS901-25 Set of 25
EUR 582

Eppendorf Centrifuge 5430R Knob Control Refrigerated- IVD Only

E5428000465 EACH
EUR 7164.9

HAV

DAG178 1 ml
EUR 754.8

HAV HAV P2C recombinant antigen

00165-V-01mg 0,1 mg
EUR 321
Description: HAV HAV P2C recombinant antigen a.a. 1121-1234.

HAV HAV P2C recombinant antigen

00165-V-1000ug 1000 ug
EUR 1539
Description: HAV HAV P2C recombinant antigen a.a. 1121-1234.

Ivd/ Rat Ivd ELISA Kit

ELI-39421r 96 Tests
EUR 1063.2

Eppendorf Centrifuge 5425R Keypad Control With Rotor Refrigerated EU-IVD

E5406000062 EACH
EUR 5434.38

Eppendorf Centrifuge 5425R Keypad Control Without Rotor Refrigerated EU-IVD

E5406000267 EACH
EUR 5055.9

Eppendorf Centrifuge 5425R Knob Control With Rotor Refrigerated EU-IVD

E5406000461 EACH
EUR 5434.38

Eppendorf Centrifuge 5425R Knob Control Without Rotor Refrigerated EU-IVD

E5406000666 EACH
EUR 5055.9

HAV Protein

abx069838-1ml 1 ml
EUR 376.8

HAV Protein

abx069839-1ml 1 ml
EUR 1178.4

HAV VP1

DAG1443 100 µg
EUR 774

HAV VP3

DAG1450 100 µg
EUR 774

HAV Antigen

E61H00101 1mg
EUR 733.2

IVD antibody

70R-18039 50 ul
EUR 522
Description: Rabbit polyclonal IVD antibody

IVD antibody

70R-13603 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal IVD antibody

IVD antibody

10R-4491 100 ul
EUR 829.2
Description: Mouse monoclonal IVD antibody

IVD antibody

22140-100ul 100ul
EUR 468

IVD siRNA

20-abx902738
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

IVD siRNA

20-abx920988
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

IVD siRNA

20-abx920989
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

IVD Antibody

DF12284 200ul
EUR 420

IVD Antibody

1-CSB-PA011921GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against IVD. Recognizes IVD from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC

IVD Antibody

1-CSB-PA011921LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against IVD. Recognizes IVD from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:500-1:1000

anti-IVD

YF-PA12811 50 ug
EUR 435.6
Description: Mouse polyclonal to IVD

anti-IVD

YF-PA12812 100 ug
EUR 483.6
Description: Rabbit polyclonal to IVD

Labcold Gel Pack for Vaccine Transport Bag

REF4120 EACH
EUR 4.22

Bordetella bronchiseptica proteins (inactivated vaccine for dog) for ELISA

BBV15-N-100 100 ug
EUR 343.2

Saponin Vaccine Adjuvant

VAdv-Ly0009 1 g
EUR 1314
Description: Saponin Vaccine Adjuvant, plant-based vaccine adjuvant.

Labcold Rigid Cool Block for Vaccine Transport Bag

REF4122 EACH
EUR 15.96

Recombinant flagellin FlicC vaccine adjuvant (TLR5 agonist); vaccine adjuvant

AV-7010-50 50 ug
EUR 1074

HAV VP3 antibody

10R-10488 100 ug
EUR 522
Description: Mouse monoclonal HAV VP3 antibody

HAV VP3 antibody

10R-10489 100 ug
EUR 522
Description: Mouse monoclonal HAV VP3 antibody

HAV VP1 antibody

10R-10520 100 ug
EUR 522
Description: Mouse monoclonal HAV VP1 antibody

HAV VP1 antibody

10R-10521 100 ug
EUR 522
Description: Mouse monoclonal HAV VP1 antibody

HAV VP1 antibody

10R-10522 100 ug
EUR 522
Description: Mouse monoclonal HAV VP1 antibody

HAV P3C Protein

abx060523-1mg 1 mg
EUR 1813.2

HAV VP1 Protein

abx060524-1mg 1 mg
EUR 1830

HAV VP3 Protein

abx060526-1mg 1 mg
EUR 1830

HAV VP3 Antibody

abx018272-100ug 100 ug
EUR 460.8

HAV VP3 Antibody

abx018273-100ug 100 ug
EUR 460.8

HAV VP1 Antibody

abx018304-100ug 100 ug
EUR 460.8

HAV VP1 Antibody

abx018305-100ug 100 ug
EUR 460.8

HAV VP1 Antibody

abx018306-100ug 100 ug
EUR 460.8

HAV P2C-P3A

DAG1448 100 µg
EUR 774

HAV VP2-VP4

DAG1451 100 µg
EUR 774

HAV monoclonal antibody

VAnt-Lsx001-1mg 1 mg
EUR 3092.4
Description: HAV, Monoclonal Antibody; contains a high concentration of viral antibody.

HAV monoclonal antibody

VAnt-Lsx001-5mg 5mg
EUR 5964
Description: HAV, Monoclonal Antibody; contains a high concentration of viral antibody.

HAV antibody (HRP)

VAnt-Lsx014-1mg 1 mg
EUR 3921.6
Description: HRP is conjugated to HAV antibody to detect the target molecule.

HAV antibody (HRP)

VAnt-Lsx014-5mg 5mg
EUR 7395.6
Description: HRP is conjugated to HAV antibody to detect the target molecule.

Human IVD Antibody

33170-05111 150 ug
EUR 313.2

IVD Polyclonal Antibody

28898-100ul 100ul
EUR 302.4

IVD Polyclonal Antibody

28898-50ul 50ul
EUR 224.4

IVD Rabbit pAb

A15281-100ul 100 ul
EUR 369.6

IVD Rabbit pAb

A15281-200ul 200 ul
EUR 550.8

IVD Rabbit pAb

A15281-20ul 20 ul
EUR 219.6

IVD Rabbit pAb

A15281-50ul 50 ul
EUR 267.6

 

 

Detection of Germline Mutations in Breast Most cancers Sufferers with Medical Options of Hereditary Most cancers Syndrome Utilizing a Multi-Gene Panel Take a look at.

 

Hereditary most cancers syndrome signifies that inherited genetic mutations can improve an individual’s danger of creating most cancers.

Tetranectin Polyclonal Antibody

 

We assessed the frequency of germline mutations utilizing an NGS-based multiple-gene panel containing 64-cancer predisposing genes in Korean breast most cancers sufferers with medical options of hereditary breast and ovarian most cancers syndrome (HBOC).A complete of 64 genes related to hereditary most cancers syndrome have been chosen for improvement of an NGS-based multi-gene panel.

Human Tetranectin (CLEC3B) ELISA Package

Focused sequencing utilizing the multi-gene panel was carried out to establish germline mutations in 496 breast most cancers sufferers with medical options of HBOC who underwent breast most cancers surgical procedure between January 2002 and December 2017.Of 496 sufferers, 95 sufferers (19.2%) have been discovered to have 48 deleterious germline mutations in 16 most cancers susceptibility genes.

Anti-Tetranectin Antibody

A08805 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Tetranectin Antibody (CLEC3B) detection.tested for IHC in Human, Mouse.

Anti-Tetranectin antibody

STJ98805 200 µl
EUR 236.4
Description: Rabbit polyclonal to Tetranectin.

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 418.8

Tetranectin Antibody

49915-100ul 100ul
EUR 399.6

Tetranectin Antibody

49915-50ul 50ul
EUR 286.8

Recombinant Human Tetranectin Protein

RP00991 10 μg
EUR 186

Tetranectin Rabbit mAb

A4387-100ul 100 ul
EUR 492

Tetranectin Rabbit mAb

A4387-200ul 200 ul
EUR 685.2

Tetranectin Rabbit mAb

A4387-20ul 20 ul
EUR 265.2

Tetranectin Rabbit mAb

A4387-50ul 50 ul
EUR 344.4

Tetranectin Conjugated Antibody

C49915 100ul
EUR 476.4

Tetranectin Polyclonal Antibody

ES8742-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Tetranectin from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA

Tetranectin Polyclonal Antibody

ES8742-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Tetranectin from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA

Tetranectin Polyclonal Antibody

46862-100ul 100ul
EUR 302.4

Tetranectin Polyclonal Antibody

46862-50ul 50ul
EUR 224.4

Tetranectin (CLEC3B) Antibody

abx145920-100ug 100 ug
EUR 469.2

Tetranectin (CLEC3B) Antibody

20-abx125686
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Tetranectin Polyclonal Antibody

ABP60656-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Tetranectin from Human, Mouse. This Tetranectin antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human Tetranectin protein at amino acid sequence of 11-60

Tetranectin Polyclonal Antibody

ABP60656-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Tetranectin from Human, Mouse. This Tetranectin antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human Tetranectin protein at amino acid sequence of 11-60

Tetranectin Polyclonal Antibody

ABP60656-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Tetranectin from Human, Mouse. This Tetranectin antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human Tetranectin protein at amino acid sequence of 11-60

Tetranectin (CLEC3B) Antibody

20-abx004912
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Tetranectin (CLEC3B) Antibody

20-abx225113
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Tetranectin (CLEC3B) Antibody

abx231752-100ug 100 ug
EUR 610.8

Tetranectin (CLEC3B) Antibody

20-abx320279
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Tetranectin Recombinant Protein

96-188 0.1 mg
EUR 682.8
Description: C-type lectin domain family 3 member B (CLEC3B) is also known as Tetranectin, Plasminogen kringle 4-binding protein, is a secreted homotrimer. CLEC3B contains 1 C-type lectin domain and mainly found in plasma. Tetranectin / CLEC3B binds to plasminogen and to isolated kringle 4. CLEC3B may be involved in the packaging of molecules destined for exocytosis. Decreased plasma Tetranectin or increased Tetranectin in stroma of cancers correlates with cancer progression and adverse prognosis.

Human Tetranectin(CLEC3B) ELISA kit

CSB-EL005531HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Tetranectin (CLEC3B) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Tetranectin(CLEC3B) ELISA kit

1-CSB-EL005531HU
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Tetranectin(CLEC3B) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Tetranectin(CLEC3B) ELISA kit

E01T0030-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Tetranectin(CLEC3B) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Tetranectin(CLEC3B) ELISA kit

E01T0030-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Tetranectin(CLEC3B) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Tetranectin(CLEC3B) ELISA kit

E01T0030-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Tetranectin(CLEC3B) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human CLEC3B/ Tetranectin ELISA Kit

E0507Hu 1 Kit
EUR 685.2

ELISA kit for Human Tetranectin

EK3337 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Tetranectin in samples from serum, plasma, tissue homogenates and other biological fluids.

Human Tetranectin (CLEC3B) ELISA Kit

abx252170-96tests 96 tests
EUR 801.6

Human CLEC3B(Tetranectin) ELISA Kit

EH0279 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Human Tetranectin/ CLEC3B ELISA Kit

ELA-E14924h 96 Tests
EUR 988.8

Human Tetranectin, CLEC3B ELISA KIT

ELI-04595h 96 Tests
EUR 988.8

Human CellExp? CLEC3B / Tetranectin, Human recombinant

P1058-10
EUR 183.6

Human CellExp? CLEC3B / Tetranectin, Human recombinant

P1058-50
EUR 601.2

Tetranectin Polyclonal Conjugated Antibody

C46862 100ul
EUR 476.4

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

Recombinant Human CLEC3B/Tetranectin (C-6His)

C453-10ug 10ug
EUR 157.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human CLEC3B/Tetranectin (C-6His)

C453-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human CLEC3B/Tetranectin (C-6His)

C453-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human CLEC3B/Tetranectin (C-6His)

C453-50ug 50ug
EUR 327.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Human Tetranectin/CLEC3B PicoKine ELISA Kit

EK1253 96 wells
EUR 510
Description: For quantitative detection of human Tetranectin in cell culture supernates and serum.

Tetranectin/CLEC3B ELISA Kit (Human) (OKBB00562)

OKBB00562 96 Wells
EUR 606
Description: Description of target: Tetranectin, also called TNA, is a protein that in humans is encoded by the CLEC3B gene. It is mapped to 3p21.31. Tetranectin, a tetrameric protein isolated from human plasma, has 4 identical and noncovalently bound polypeptide chains, each of 181 amino acid residues. It has a specific binding affinity for sulfated polysaccharides and the kringle 4 of plasminogen. The plasma concentration of tetranectin is reduced in patients with various malignancies. Tetranectin is a plasminogen-binding protein that is induced during the mineralization phase of osteogenesis. Thus, tetranectin is a candidate gene for human disorders affecting bone and connective tissue.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Mouse Tetranectin(CLEC3B) ELISA kit

CSB-EL005531MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Tetranectin (CLEC3B) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Tetranectin(CLEC3B) ELISA kit

1-CSB-EL005531MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Tetranectin(CLEC3B) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Clec3b/ Tetranectin ELISA Kit

E0296Mo 1 Kit
EUR 685.2

Rabbit Tetranectin(CLEC3B) ELISA kit

E04T0030-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Tetranectin(CLEC3B) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Tetranectin(CLEC3B) ELISA kit

E04T0030-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Tetranectin(CLEC3B) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Tetranectin(CLEC3B) ELISA kit

E04T0030-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Tetranectin(CLEC3B) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

The deleterious mutations have been present in 39 of 250 sufferers (15.6%) who had breast most cancers and one other main most cancers, 38 of 169 sufferers (22.5%) who had a household historical past of breast most cancers (≥ 2 family members), 16 of 57 sufferers (28.1%) who had bilateral breast most cancers, and 29 of 84 sufferers (34.5%) who have been recognized with breast most cancers at youthful than 40 years of age.

Human CellExp? CLEC3B / Tetranectin, Human recombinant

Of the 95 sufferers with deleterious mutations, 60 sufferers (63.2%) had BRCA1/2 mutations and 38 sufferers (40.0%) had non-BRCA1/2 mutations. We detected 2 novel deleterious mutations in BRCA2 and MLH1.NGS-based multiple-gene panel testing improved the detection charges of deleterious mutations and supplied a cheap most cancers danger evaluation.