Validation and comparability of luminex multiplex cytokine evaluation kits with ELISA: determinations of a panel of 9 cytokines in scientific pattern tradition supernatants.
OBJECTIVE
Analyses of the expression sample of a number of cytokines are incessantly required for characterization of the standing of the immune system because it pertains to Th kind bias and intrinsic ranges of irritation. Classically, evaluation of cytokine expression patterns has been carried out by enzyme-linked immunosorbent assays (ELISA) for every separate analyte.
A brand new expertise, Luminex MAP, facilitates the simultaneous analysis of a number of immune mediators with benefits of upper throughput, smaller pattern quantity, and decrease price. Validation of this expertise has been restricted to small pattern units, restricted use of scientific research specimens, and use of non-commercial reagents.
COLISTIN METHANESULFONATE (SODIUM SALT)
METHODS
Ninety-six specimens from ladies over the course of their respective pregnancies had been evaluated for cytokine concentrations utilizing commercially obtainable ELISA kits and commercially available Luminex MAP kits according to the producers’ instructions. Correlations between information units had been evaluated utilizing Pearson’s correlation coefficient (r).
RESULTS
Wonderful correlations were demonstrated for IL-1 beta, IL-4, IL-5, IL-6, IL-10, IFN gamma, and TNF alpha, in distinction to IL-12 p 70 and IL-13.
COLISTIN SODIUM METHANESULFONATE
CONCLUSIONS
Luminex multiplex expertise has distinct benefits and is a sound various technique to ELISA for the analysis of the vast majority of cytokines examined and for the characterization of immune system standing.
Imatinib, Methanesulfonate Salt, >99% |
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BC040-101 | GenDepot | 1g | EUR 278.4 |
Imatinib, Methanesulfonate Salt, >99% |
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BC040-102 | GenDepot | 2g | EUR 360 |
Imatinib, Methanesulfonate Salt, >99% |
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BC040-105 | GenDepot | 5g | EUR 505.2 |
Imatinib, Methanesulfonate Salt, >99% |
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BC040-500 | GenDepot | 500mg | Ask for price |
Colistin Methanesulfonate (sodium salt) |
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C3046-1000 | ApexBio | 1 g | EUR 208.8 |
Colistin Methanesulfonate (sodium salt) |
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C3046-5000 | ApexBio | 5 g | EUR 734.4 |
Ethyl methanesulfonate |
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20-abx186442 | Abbexa |
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Ethyl methanesulfonate |
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GX0446-100G | Glentham Life Sciences | 100 g | EUR 313.2 |
Ethyl methanesulfonate |
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GX0446-10G | Glentham Life Sciences | 10 g | EUR 88.8 |
Ethyl methanesulfonate |
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GX0446-25G | Glentham Life Sciences | 25 g | EUR 141.6 |
Ethyl methanesulfonate |
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GX0446-5G | Glentham Life Sciences | 5 g | EUR 64.8 |
Ethyl methanesulfonate |
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S-1930 | Scientific Laboratory Supplies | 1ML | EUR 84 |
Ethyl methanesulfonate |
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GX0446-10 | Glentham Life Sciences | 10 | EUR 43.5 |
Ethyl methanesulfonate |
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GX0446-100 | Glentham Life Sciences | 100 | EUR 229.3 |
Ethyl methanesulfonate |
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GX0446-25 | Glentham Life Sciences | 25 | EUR 87.1 |
Ethyl methanesulfonate |
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GX0446-5 | Glentham Life Sciences | 5 | EUR 23.8 |
BCX 1470 (methanesulfonate) |
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HY-50875 | MedChemExpress | 10mM/1mL | EUR 696 |
Silver methanesulfonate |
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GX5020-25G | Glentham Life Sciences | 25 g | EUR 208.8 |
Silver methanesulfonate |
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GX5020-5G | Glentham Life Sciences | 5 g | EUR 85.2 |
Silver methanesulfonate |
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GX5020-25 | Glentham Life Sciences | 25 | EUR 142.4 |
Silver methanesulfonate |
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GX5020-5 | Glentham Life Sciences | 5 | EUR 40.3 |
Pridinol Methanesulfonate |
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A8507-1000 | ApexBio | 1 g | EUR 517.2 |
Pridinol Methanesulfonate |
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A8507-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 129.6 |
Pridinol Methanesulfonate |
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A8507-50 | ApexBio | 50 mg | EUR 153.6 |
Pridinol Methanesulfonate |
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A8507-5000 | ApexBio | 5 g | EUR 1198.8 |
Tricaine methanesulfonate |
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GE5936-10G | Glentham Life Sciences | 10 g | EUR 68.4 |
Tricaine methanesulfonate |
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GE5936-25G | Glentham Life Sciences | 25 g | EUR 98.4 |
Tricaine methanesulfonate |
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GE5936-50G | Glentham Life Sciences | 50 g | EUR 141.6 |
Tricaine methanesulfonate |
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GE5936-5G | Glentham Life Sciences | 5 g | EUR 56.4 |
Tricaine methanesulfonate |
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GE5936-10 | Glentham Life Sciences | 10 | EUR 26.9 |
Tricaine methanesulfonate |
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GE5936-25 | Glentham Life Sciences | 25 | EUR 51.4 |
Tricaine methanesulfonate |
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GE5936-5 | Glentham Life Sciences | 5 | EUR 16.6 |
Tricaine methanesulfonate |
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GE5936-50 | Glentham Life Sciences | 50 | EUR 87.1 |
Ro 31-8220 methanesulfonate |
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1946-1 | Biovision | each | EUR 164.4 |
Ro 31-8220 methanesulfonate |
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1946-5 | Biovision | each | EUR 457.2 |
Abemaciclib (methanesulfonate) |
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HY-16297 | MedChemExpress | 500mg | EUR 542.4 |
PF-04217903 methanesulfonate |
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A3712-100 | ApexBio | 100 mg | EUR 714 |
PF-04217903 methanesulfonate |
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A3712-25 | ApexBio | 25 mg | EUR 351.6 |
PF-04217903 methanesulfonate |
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A3712-5 | ApexBio | 5 mg | EUR 157.2 |
PF-06424439 (methanesulfonate) |
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HY-108341A | MedChemExpress | 10mM/1mL | EUR 175.2 |
PF-04217903 (methanesulfonate) |
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HY-12017A | MedChemExpress | 10mM/1mL | EUR 187.2 |
2-Chloroethyl methanesulfonate |
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20-abx183170 | Abbexa |
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Colistin Sodium Methanesulfonate |
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C073-10G | TOKU-E | 10 g | EUR 984 |
Colistin Sodium Methanesulfonate |
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C073-1G | TOKU-E | 1 g | EUR 162 |
Colistin Sodium Methanesulfonate |
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C073-5G | TOKU-E | 5 g | EUR 528 |
Colistin sodium methanesulfonate |
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GA2961-1G | Glentham Life Sciences | 1 g | EUR 151.2 |
Colistin sodium methanesulfonate |
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GA2961-5G | Glentham Life Sciences | 5 g | EUR 351.6 |
Colistin sodium methanesulfonate |
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GA2961-1 | Glentham Life Sciences | 1 | EUR 95 |
Colistin sodium methanesulfonate |
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GA2961-5 | Glentham Life Sciences | 5 | EUR 261 |
Tariquidar methanesulfonate, hydrate |
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A3859-10 | ApexBio | 10 mg | EUR 226.8 |
Tariquidar methanesulfonate, hydrate |
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A3859-50 | ApexBio | 50 mg | EUR 532.8 |
Tariquidar (methanesulfonate, hydrate) |
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HY-10550A | MedChemExpress | 100mg | EUR 734.4 |
Hydroxystilbamidine bis(methanesulfonate) |
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HY-108166A | MedChemExpress | 5mg | EUR 639.6 |
Hydroxystilbamidine bis(methanesulfonate) |
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GW9028-10 | Glentham Life Sciences | 10 | EUR 405.4 |
Ethyl 3-Aminobenzoate (methanesulfonate) |
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C3619-100000 | ApexBio | 100 g | EUR 381.6 |
Ethyl 3-Aminobenzoate (methanesulfonate) |
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C3619-25000 | ApexBio | 25 g | EUR 153.6 |
Ethyl 3-Aminobenzoate (methanesulfonate) |
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C3619-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Ethyl 3-Aminobenzoate (methanesulfonate) |
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C3619-50000 | ApexBio | 50 g | EUR 234 |
Pesticide Std Methyl Methanesulfonate Neat |
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REPET374N | Scientific Laboratory Supplies | 10MG | EUR 91.39 |
Pesticide Std Ethyl methanesulfonate Neat |
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REPET352N | Scientific Laboratory Supplies | 10MG | EUR 91.39 |
Pesticide Std Methyl Methanesulfonate 1000ug/mL in MeOH |
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REPET374 | Scientific Laboratory Supplies | 1ML | EUR 122.73 |
Pesticide Std Methyl Methanesulfonate 2000ug/mL in MeOH |
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REPET375 | Scientific Laboratory Supplies | 1ML | EUR 118.81 |
Pesticide Std Ethyl methanesulfonate 1000ug/mL in MeOH |
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REPET352 | Scientific Laboratory Supplies | 1ML | EUR 110.98 |
Pesticide Std Ethyl methanesulfonate 2000ug/mL in MeOH |
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REPET353 | Scientific Laboratory Supplies | 1ML | EUR 124.03 |
Dabrafenib |
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20-abx182412 | Abbexa |
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Dabrafenib |
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D072-10MG | TOKU-E | 10 mg | EUR 159.6 |
Dabrafenib |
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D072-25MG | TOKU-E | 25 mg | EUR 266.4 |
Dabrafenib |
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HY-14660 | MedChemExpress | 100mg | EUR 253.2 |
METHANESULFONIC ACID SODIUM SALT |
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713003 | Survival Technologies | each | Ask for price |
Dabrafenib (Mesylate) |
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HY-14660A | MedChemExpress | 10mM/1mL | EUR 153.6 |
Dabrafenib (GSK2118436) |
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B1407-10 | ApexBio | 10 mg | EUR 157.2 |
Dabrafenib (GSK2118436) |
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B1407-100 | ApexBio | 100 mg | EUR 393.6 |
Dabrafenib (GSK2118436) |
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B1407-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Dabrafenib (GSK2118436) |
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B1407-50 | ApexBio | 50 mg | EUR 268.8 |
Ethyl 3-aminobenzoate, methanesulfonic acid salt |
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20-abx184051 | Abbexa |
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Methanesulfonic acid,1,1,1-trifluoro-, mercury(2+) salt (2:1) |
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20-abx184173 | Abbexa |
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Dabrafenib Mesylate (GSK-2118436) |
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A3347-10 | ApexBio | 10 mg | EUR 157.2 |
Dabrafenib Mesylate (GSK-2118436) |
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A3347-100 | ApexBio | 100 mg | EUR 393.6 |
Dabrafenib Mesylate (GSK-2118436) |
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A3347-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 150 |
Dabrafenib Mesylate (GSK-2118436) |
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A3347-50 | ApexBio | 50 mg | EUR 268.8 |
Dabrafenib Mesylate (GSK-2118436) |
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A3347-S | ApexBio | Evaluation Sample | EUR 97.2 |
METHANESULFONAMIDE |
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913003 | Survival Technologies | each | Ask for price |
N-Methyl methanesulfonamide |
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20-abx185872 | Abbexa |
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N-(3-Formylphenyl)Methanesulfonamide |
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abx188797-25g | Abbexa | 25 g | EUR 1045.2 |
Methanesulfonic acid |
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GK8835-25G | Glentham Life Sciences | 25 g | EUR 55.2 |
Methanesulfonic acid |
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S-2378 | Scientific Laboratory Supplies | 1ML | EUR 97.2 |
Methanesulfonic acid |
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GK8835-25 | Glentham Life Sciences | 25 | EUR 16.1 |
Purposeful evaluation of the classical, various, and MBL pathways of the complement system: standardization and validation of a easy ELISA.
- Major defence towards invading microorganisms depends upon a practical innate immune system and the complement system performs a serious position in such immunity.
- Deficiencies in one of many parts of the complement system may cause extreme and recurrent infections, systemic ailments, akin to systemic lupus erythematosus (SLE) and renal illness.
Rapamycin |
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20-abx185560 | Abbexa |
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Rapamycin |
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1568-5 | Biovision | each | EUR 339.6 |
Rapamycin |
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1568-50 | Biovision | each | EUR 1396.8 |
Rapamycin |
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27062 | BPS Bioscience | 50 mg | EUR 135 |
Rapamycin |
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20-abx076788 | Abbexa |
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Rapamycin |
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GA7417-100MG | Glentham Life Sciences | 100 mg | EUR 274.8 |
Rapamycin |
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GA7417-25MG | Glentham Life Sciences | 25 mg | EUR 112.8 |
Rapamycin |
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GA7417-50MG | Glentham Life Sciences | 50 mg | EUR 180 |
Rapamycin |
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GA7417-5MG | Glentham Life Sciences | 5 mg | EUR 64.8 |
Rapamycin |
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E1B1842 | EnoGene | 1mg | EUR 153.6 |
Rapamycin |
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HY-10219 | MedChemExpress | 200mg | EUR 241.2 |
Rapamycin |
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R001-10MG | TOKU-E | 10 mg | EUR 243.6 |
Rapamycin |
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R001-25MG | TOKU-E | 25 mg | EUR 295.2 |
Rapamycin |
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GA7417-100 | Glentham Life Sciences | 100 | EUR 197.7 |
Rapamycin |
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GA7417-25 | Glentham Life Sciences | 25 | EUR 63.3 |
Rapamycin |
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GA7417-5 | Glentham Life Sciences | 5 | EUR 23.8 |
Rapamycin |
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GA7417-50 | Glentham Life Sciences | 50 | EUR 118.7 |
Rapamycin, 100mg |
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R5312-100mg | ACTGene | each | EUR 902.4 |
Rapamycin, >99% |
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BC082-050 | GenDepot | 50mg | EUR 262.8 |
Rapamycin, >99% |
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BC082-100 | GenDepot | 100mg | EUR 313.2 |
Rapamycin, >99% |
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BC082-250 | GenDepot | 250mg | EUR 424.8 |
Rapamycin, >99% |
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BC082-500 | GenDepot | 500mg | EUR 651.6 |
Seco Rapamycin |
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HY-19555 | MedChemExpress | 50mg | EUR 2704.8 |
Rapamycin, 10mg |
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R5312-10mg | ACTGene | each | EUR 244.8 |
Rapamycin (Sirolimus) |
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A8167-100 | ApexBio | 100 mg | EUR 616.8 |
Rapamycin (Sirolimus) |
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A8167-25 | ApexBio | 25 mg | EUR 268.8 |
Rapamycin (Sirolimus) |
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A8167-5 | ApexBio | 5 mg | EUR 129.6 |
Rapamycin (Sirolimus) |
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A8167-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 351.6 |
Rapamycin (Sirolimus) |
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A8167-S | ApexBio | Evaluation Sample | EUR 97.2 |
Rapamycin (Sirolimus) |
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E1KS1039 | EnoGene | 50mg | EUR 247.2 |
EZSolution? Rapamycin |
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1746-5 | Biovision | each | EUR 326.4 |
Rapamycin (mTOR inhibitor) |
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SIH-212-25MG | Stressmarq | 25 mg | EUR 490.8 |
Rapamycin (mTOR inhibitor) |
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SIH-212-5MG | Stressmarq | 5 mg | EUR 242.4 |
Seco Rapamycin (sodium salt) |
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HY-19555A | MedChemExpress | 1mg | EUR 207.6 |
42-(2-Tetrazolyl)rapamycin |
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HY-12424A | MedChemExpress | 1mg | EUR 241.2 |
Dog Mammalian target of rapamycin ELISA kit |
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E08M0019-192T | BlueGene | 192 tests | EUR 1524 |
Dog Mammalian target of rapamycin ELISA kit |
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E08M0019-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Dog Mammalian target of rapamycin ELISA kit |
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E08M0019-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Rat Mammalian target of rapamycin ELISA kit |
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E02M0019-192T | BlueGene | 192 tests | EUR 1524 |
Rat Mammalian target of rapamycin ELISA kit |
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E02M0019-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Rat Mammalian target of rapamycin ELISA kit |
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E02M0019-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Pig Mammalian target of rapamycin ELISA kit |
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E07M0019-192T | BlueGene | 192 tests | EUR 1524 |
Pig Mammalian target of rapamycin ELISA kit |
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E07M0019-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Pig Mammalian target of rapamycin ELISA kit |
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E07M0019-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Goat Mammalian target of rapamycin ELISA kit |
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E06M0019-192T | BlueGene | 192 tests | EUR 1524 |
Goat Mammalian target of rapamycin ELISA kit |
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E06M0019-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Goat Mammalian target of rapamycin ELISA kit |
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E06M0019-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Mouse Mammalian target of rapamycin ELISA kit |
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E03M0019-192T | BlueGene | 192 tests | EUR 1524 |
Mouse Mammalian target of rapamycin ELISA kit |
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E03M0019-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Mouse Mammalian target of rapamycin ELISA kit |
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E03M0019-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Human Mammalian target of rapamycin ELISA kit |
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E01M0019-192T | BlueGene | 192 tests | EUR 1524 |
Human Mammalian target of rapamycin ELISA kit |
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E01M0019-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Human Mammalian target of rapamycin ELISA kit |
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E01M0019-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Rabbit Mammalian target of rapamycin ELISA kit |
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E04M0019-192T | BlueGene | 192 tests | EUR 1524 |
Rabbit Mammalian target of rapamycin ELISA kit |
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E04M0019-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Rabbit Mammalian target of rapamycin ELISA kit |
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E04M0019-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Monkey Mammalian target of rapamycin ELISA kit |
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E09M0019-192T | BlueGene | 192 tests | EUR 1524 |
Monkey Mammalian target of rapamycin ELISA kit |
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E09M0019-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Monkey Mammalian target of rapamycin ELISA kit |
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E09M0019-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Rat mammalian target of rapamycin(mTOR)ELISA Kit |
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GA-E0434RT-48T | GenAsia Biotech | 48T | EUR 380.4 |
Rat mammalian target of rapamycin(mTOR)ELISA Kit |
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GA-E0434RT-96T | GenAsia Biotech | 96T | EUR 595.2 |
Rat mammalian target of rapamycin(mTOR)ELISA Kit |
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QY-E11218 | Qayee Biotechnology | 96T | EUR 433.2 |
Rat Mammalian Target of Rapamycin(mTOR)ELISA Kit |
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YLA1487RA-48T | Shanghai YL Biotech | 48T | EUR 465 |
Rat Mammalian Target of Rapamycin(mTOR)ELISA Kit |
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YLA1487RA-96T | Shanghai YL Biotech | 96T | EUR 600 |
Human Mammalian Target of Rapamycin (mTOR) CLIA Kit |
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abx195664-96tests | Abbexa | 96 tests | EUR 990 |
Guinea pig Mammalian target of rapamycin ELISA kit |
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E05M0019-192T | BlueGene | 192 tests | EUR 1524 |
Guinea pig Mammalian target of rapamycin ELISA kit |
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E05M0019-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Guinea pig Mammalian target of rapamycin ELISA kit |
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E05M0019-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Mouse mammalian target of rapamycin(mTOR)ELISA Kit |
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QY-E20962 | Qayee Biotechnology | 96T | EUR 433.2 |
Mouse Mammalian Target of Rapamycin(mTOR)ELISA Kit |
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YLA1811MO-48T | Shanghai YL Biotech | 48T | EUR 465 |
Mouse Mammalian Target of Rapamycin(mTOR)ELISA Kit |
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YLA1811MO-96T | Shanghai YL Biotech | 96T | EUR 600 |
Human Mammalian Target of Rapamycin(mTOR)ELISA Kit |
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YLA1299HU-48T | Shanghai YL Biotech | 48T | EUR 435 |
Human Mammalian Target of Rapamycin(mTOR)ELISA Kit |
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YLA1299HU-96T | Shanghai YL Biotech | 96T | EUR 562.5 |
Mechanistic Target of Rapamycin Kinase (mTOR) Antibody |
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20-abx133144 | Abbexa |
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Mechanistic Target Of Rapamycin Kinase (MTOR) Antibody |
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abx331921-100ul | Abbexa | 100 ul | EUR 510 |
Mechanistic Target Of Rapamycin Kinase (MTOR) Antibody |
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abx331979-100ul | Abbexa | 100 ul | EUR 510 |
Mechanistic Target of Rapamycin Kinase (MTOR) Antibody |
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abx038215-100ug | Abbexa | 100 ug | EUR 469.2 |
Mechanistic Target of Rapamycin Kinase (mTOR) Antibody |
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20-abx009248 | Abbexa |
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CLIA kit for Human mTOR (Mammalian Target of Rapamycin) |
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E-CL-H1050 | Elabscience Biotech | 1 plate of 96 wells | EUR 700.8 |
ELISA kit for Human mTOR (Mammalian Target of Rapamycin) |
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E-EL-H1655 | Elabscience Biotech | 1 plate of 96 wells | EUR 640.8 |
Target of Rapamycin Complex Subunit LST8 (MLST8) Antibody |
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abx117025-100ug | Abbexa | 100 ug | EUR 560.4 |
Target of rapamycin complex subunit LST8 (MLST8) Antibody |
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20-abx333910 | Abbexa |
|
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Target of Rapamycin Complex Subunit LST8 (MLST8) Antibody |
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20-abx000982 | Abbexa |
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Target of rapamycin complex subunit LST8 (MLST8) Antibody (HRP) |
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20-abx337874 | Abbexa |
|
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Rat Target of rapamycin complex subunit LST8 (MLST8) ELISA Kit |
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abx391633-96tests | Abbexa | 96 tests | EUR 1093.2 |
Target of rapamycin complex subunit LST8 (MLST8) Antibody (FITC) |
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20-abx337875 | Abbexa |
|
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Human Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1) |
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1-CSB-EP857767HU | Cusabio |
|
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Mouse Target of rapamycin complex subunit LST8 (MLST8) ELISA Kit |
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abx389931-96tests | Abbexa | 96 tests | EUR 1093.2 |
Human Target of rapamycin complex subunit LST8 (MLST8) ELISA Kit |
|||
abx385173-96tests | Abbexa | 96 tests | EUR 1093.2 |
Human Target of rapamycin complex subunit LST8, MLST8 ELISA KIT |
|||
ELI-37344h | Lifescience Market | 96 Tests | EUR 988.8 |
- Screening for complement deficiencies within the classical or various complement pathways has primarily been carried out by haemolytic assays. Right here, we describe a easy ELISA-based format for the analysis of three pathways of complement activation. The assays are primarily based on particular coatings for every pathway together with particular buffer methods.
Mouse Mammalian goal of rapamycin ELISA package
- We’ve got standardized these assays and outlined minimize off values to detect complement deficiencies on the completely different ranges of the complement system. The outcomes display the worth of those ELISA-based procedures for the practical evaluation of complement deficiencies in scientific follow. The assay is now obtainable commercially in package kind.
- On this research we examined the timecourse of induction of brain-derived neurotrophic issue (BDNF) mRNA and protein after 1, 3, 5, 7, 14 and 28 days of train within the rat.
- To measure the expression of mRNA for particular person BDNF exons we utilized a semi-quantitative RT–PCR method, whereas BDNF protein was assessed utilizing business ELISA kits. We demonstrated that the gap run by animals elevated considerably (P<0.05) after Four weeks. BDNF protein was considerably (P<0.05) elevated after Four weeks of train, whereas the mRNA for particular person BDNF exons elevated considerably (P<0.05) over the timecourse (exon I after 1 and 28 days and exons II and V after 28 days).
- The Morris water maze was then utilized to display that Three weeks of prior train enhanced the speed of studying on this process. Train, due to this fact, was proven to modulate BDNF induction in a time-dependent method, and this may increasingly translate to enhancements in neurotrophin-mediated duties throughout the CNS.