Chemical nano-gardens: progress of salt nanowires from supramolecular self-assembly gels.
- On this article, we study the phenomenon of single-crystal halide salt wire progress at the floor of porous supplies. We report the usage of a single-step casting method with a supramolecular self-assembly gel matrix that upon drying results in the expansion of single-crystal halide (e.g., NaCl, KCl, and KI) nanowires with diameters ~130-200 nm.
CARUBICIN (FREE BASE) | TERBINAFINE (FREE BASE)
- We display their formation utilizing electron microscopy and electron-dispersive X-ray spectroscopy, exhibiting that the supramolecular gel stabilizes the expansion of those wires by facilitating a diffusion-driven base progress mechanism.
- Critically, we present that commonplace non-supramolecular gels are unable to facilitate nanowire progress. We additional present that these nanowires may be grown by seeding, forming nanocrystal gardens. This research helps perceive the potential prefunctionalization of membranes to stimulate ion-specific filters or salt efflorescence suppressors, whereas additionally offering a novel route to nanomaterial progress.
- Aloe vera has been acknowledged as a invaluable medicinal plant for the therapy of burns. In depth research have described its antiinflammatory, wound therapeutic and associated actions, however the instability of aloe gel confuses pharmacological knowledge, results in inconsistency in therapies and inconvenience in every day preparation.
IXABEPILONE, FREE BASE | GEL CASTING BASE 20 CM
- These obstacles prompted us to develop a stable aloe preparation, aloe cream, that we examined on synthetic thermal burns in mice. Aloe cream when utilized instantly to first diploma burns delayed progressive injury and accelerated the healing charge extra successfully than contemporary aloe gel. Each aloe cream and contemporary aloe gel prevented additional pores and skin injury and casting of lifeless dermis was lower than in management.
- For second diploma burns the therapeutic charge was enhanced by aloe cream and contemporary aloe gel: much less irritation was noticed in areas handled with both of those than in untreated areas or these handled with the cream base. For third diploma burns the efficacy of aloe cream and contemporary aloe gel couldn’t be evaluated statistically due to an infection.
- It was noticed that aloe cream enhanced epithelialization however failed to point out antiinflammatory activity. No variations in epithelialization and irritation had been noticed amongst mice handled with contemporary aloe gel, cream base or management. All these findings verify that Aloe vera gel is efficient for burn therapy whether it is properly preserved.
Human Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) |
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| 1-CSB-EP013175HU(B) | Cusabio |
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Human Plexin-A1 (PLXNA1) |
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| 1-CSB-RP143094h(B) | Cusabio |
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Epothilone B |
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| 2012-1 | Biovision | EUR 164.4 | |
Epothilone B |
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| 2012-5 | Biovision | EUR 464.4 | |
Epothilone B |
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| 20-abx076606 | Abbexa |
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Epothilone B |
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| ADC-P-087 | Creative Biolabs | unit | Ask for price |
Epothilone B |
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| E047-0.1MG | TOKU-E | 0.1 mg | EUR 381.6 |
Epothilone B |
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| E047-0.5MG | TOKU-E | 0.5 mg | EUR 1248 |
Epothilone B |
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| E1KS1364 | EnoGene | 5mg | EUR 625.2 |
Epothilone B |
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| HY-17029 | MedChemExpress | 10mM/1mL | EUR 189.6 |
gel casting base 10 cm |
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| EVS1100-BASE | Consort | ea | EUR 180 |
gel casting base 20 cm |
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| EVS1300-BASE | Consort | ea | EUR 240 |
gel casting base for evs3100 |
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| EVS3100-BASE | Consort | ea | EUR 361.2 |
gel casting base for evs3200 |
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| EVS3200-BASE | Consort | ea | EUR 361.2 |
gel casting base for evs3300 |
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| EVS3300-BASE | Consort | ea | EUR 361.2 |
Vatalanib, Free Base |
|||
| 2026-25 | Biovision | EUR 366 | |
Vatalanib, Free Base |
|||
| 2026-5 | Biovision | EUR 151.2 | |
Erlotinib, Free Base |
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| 2048-100 | Biovision | EUR 189.6 | |
Erlotinib, Free Base |
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| 2048-1000 | Biovision | EUR 464.4 | |
Sunitinib, Free base |
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| 2097-100 | Biovision | EUR 229.2 | |
Sunitinib, Free base |
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| 2097-1000 | Biovision | EUR 601.2 | |
Sunitinib, Free base |
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| 2097-25 | Biovision | EUR 138 | |
Ruxolitinib (free base) |
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| 10-042 | ProSci | 25 mg | EUR 418.2 |
Lapatinib, Free base |
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| 2138-100 | Biovision | EUR 464.4 | |
Lapatinib, Free base |
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| 2138-25 | Biovision | EUR 229.2 | |
Ruxolitinib, Free base |
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| 2139-100 | Biovision | Ask for price | |
Ruxolitinib, Free base |
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| 2139-25 | Biovision | EUR 639.6 | |
Ruxolitinib, Free base |
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| 2139-5 | Biovision | EUR 248.4 | |
Imatinib, Free base |
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| 2141-100 | Biovision | EUR 176.4 | |
Imatinib, Free base |
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| 2141-1000 | Biovision | EUR 502.8 | |
Linsitinib, Free base |
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| 2294-25 | Biovision | EUR 679.2 | |
Linsitinib, Free base |
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| 2294-5 | Biovision | EUR 222 | |
Tipifarnib, Free base |
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| 2296-1 | Biovision | EUR 170.4 | |
Tipifarnib, Free base |
|||
| 2296-5 | Biovision | EUR 496.8 | |
Rucaparib (free base) |
|||
| A8893-10 | ApexBio | 10 mg | EUR 240 |
Rucaparib (free base) |
|||
| A8893-200 | ApexBio | 200 mg | EUR 1243.2 |
Rucaparib (free base) |
|||
| A8893-5 | ApexBio | 5 mg | EUR 164.4 |
Rucaparib (free base) |
|||
| A8893-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 170.4 |
Rucaparib (free base) |
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| A8893-50 | ApexBio | 50 mg | EUR 547.2 |
LY2835219 free base |
|||
| A3575-100 | ApexBio | 100 mg | EUR 686.4 |
LY2835219 free base |
|||
| A3575-25 | ApexBio | 25 mg | EUR 309.6 |
LY2835219 free base |
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| A3575-5 | ApexBio | 5 mg | EUR 170.4 |
R406 (free base) |
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| A5880-100 | ApexBio | 100 mg | EUR 1452 |
R406 (free base) |
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| A5880-25 | ApexBio | 25 mg | EUR 616.8 |
R406 (free base) |
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| A5880-5 | ApexBio | 5 mg | EUR 199.2 |
R406 (free base) |
|||
| A5880-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 316.8 |
R406 (free base) |
|||
| A5880-S | ApexBio | Evaluation Sample | EUR 97.2 |
THZ1 (Free base) |
|||
| 9664-25 | Biovision | EUR 1227.6 | |
THZ1 (Free base) |
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| 9664-5 | Biovision | EUR 352.8 | |
MCC950 (Free base) |
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| B1031-1 | Biovision | EUR 183.6 | |
MCC950 (Free base) |
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| B1031-5 | Biovision | EUR 548.4 | |
FIPI (free base) |
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| B2372-25 | Biovision | EUR 757.2 | |
FIPI (free base) |
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| B2372-5 | Biovision | EUR 235.2 | |
Terbinafine (Free base) |
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| B2423-250 | Biovision | EUR 248.4 | |
Terbinafine (Free base) |
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| B2423-50 | Biovision | EUR 144 | |
PLX5622 (free base) |
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| B2965-25 | Biovision | 25 mg | EUR 903.6 |
PLX5622 (free base) |
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| B2965-5 | Biovision | 5 mg | EUR 272.4 |
Apatinib (Free base) |
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| B1613-25 | Biovision | EUR 496.8 | |
Apatinib (Free base) |
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| B1613-5 | Biovision | EUR 170.4 | |
Carubicin (Free base) |
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| B1853-1 | Biovision | EUR 183.6 | |
Carubicin (Free base) |
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| B1853-5 | Biovision | EUR 548.4 | |
AZD4547, Free Base |
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| ADC-P-063 | Creative Biolabs | unit | Ask for price |
AZD8055, Free Base |
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| ADC-P-064 | Creative Biolabs | unit | Ask for price |
Cyclopamine, Free Base |
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| ADC-P-079 | Creative Biolabs | unit | Ask for price |
Ixabepilone, Free Base |
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| ADC-P-104 | Creative Biolabs | unit | Ask for price |
R406(free base) |
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| E1KS1533 | EnoGene | 2mg | EUR 625.2 |
Ripasudil free base |
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| HY-15685A | MedChemExpress | 10mg | EUR 489.6 |
Vatalanib (free base) |
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| HY-10203 | MedChemExpress | 5mg | EUR 142.8 |
RPR107393 free base |
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| HY-100299 | MedChemExpress | 1mg | EUR 577.2 |
FR167344 free base |
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| HY-100301 | MedChemExpress | 1mg | EUR 3164.4 |
FR183998 free base |
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| HY-100302 | MedChemExpress | 1mg | EUR 1352.4 |
FR194738 free base |
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| HY-100303 | MedChemExpress | 1mg | EUR 2388 |
YM158 (free base) |
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| HY-U00355 | MedChemExpress | 1mg | EUR 2770.8 |
Masupirdine (free base) |
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| HY-109118 | MedChemExpress | 1mg | EUR 267.6 |
R406 (free base) |
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| HY-11108 | MedChemExpress | 10mM/1mL | EUR 277.2 |
ITI214 (free base) |
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| HY-12501 | MedChemExpress | 100mg | EUR 3531.6 |
AS2863619 (free base) |
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| HY-126675 | MedChemExpress | 5mg | EUR 1410 |
A Biomimetic Urethral Mannequin to Consider Urinary Catheter Lubricity and Epithelial Micro-Trauma
-
The usual technique of evaluating the lubricity of intermittent urinary catheters with coefficient of friction (CoF) testing shouldn’t be physiologically related, whereas there’s additionally a dearth of printed analysis on catheter-associated urethral micro-trauma. We developed a novel human urethral epithelial cell-seeded mannequin of the urethra to switch the rubber counter-surface utilized in commonplace CoF testing.
ERLOTINIB, FREE BASE | MCC950 (FREE BASE)
-
This cell-seeded mannequin, at the side of a novel testing system, permits an investigation of catheter-associated epithelial micro-trauma in vitro for the primary time. The CoF of 4 manufacturers of commercially-available hydrophilic-coated intermittent catheters was measured utilizing each the rubber and urethral mannequin counter-surfaces.bodel, the injury to the epithelial layer was analysed utilizing commonplace cell imaging.
-
The rubber counter-surface was proven to over-estimate the CoF of gel-coated catheters in comparison with our urethral mannequin because of stick-slip behaviour attributable to polymer-on-polymer interplay of the catheter base material on the rubber counter-surface. We recognized no deleterious impact as a result of presence or design of catheter eyelets to both the CoF measurements or the diploma of epithelium injury in our mannequin.
gel casting base 10 cm |
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| EVS1100-BASE | Consort | ea | EUR 180 |
gel casting base 20 cm |
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| EVS1300-BASE | Consort | ea | EUR 240 |
gel casting base for evs3100 |
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| EVS3100-BASE | Consort | ea | EUR 361.2 |
gel casting base for evs3200 |
|||
| EVS3200-BASE | Consort | ea | EUR 361.2 |
gel casting base for evs3300 |
|||
| EVS3300-BASE | Consort | ea | EUR 361.2 |
Vatalanib, Free Base |
|||
| 2026-25 | Biovision | EUR 366 | |
Vatalanib, Free Base |
|||
| 2026-5 | Biovision | EUR 151.2 | |
Erlotinib, Free Base |
|||
| 2048-100 | Biovision | EUR 189.6 | |
Erlotinib, Free Base |
|||
| 2048-1000 | Biovision | EUR 464.4 | |
Sunitinib, Free base |
|||
| 2097-100 | Biovision | EUR 229.2 | |
Sunitinib, Free base |
|||
| 2097-1000 | Biovision | EUR 601.2 | |
Sunitinib, Free base |
|||
| 2097-25 | Biovision | EUR 138 | |
Ruxolitinib (free base) |
|||
| 10-042 | ProSci | 25 mg | EUR 418.2 |
Lapatinib, Free base |
|||
| 2138-100 | Biovision | EUR 464.4 | |
Lapatinib, Free base |
|||
| 2138-25 | Biovision | EUR 229.2 | |
Ruxolitinib, Free base |
|||
| 2139-100 | Biovision | Ask for price | |
Ruxolitinib, Free base |
|||
| 2139-25 | Biovision | EUR 639.6 | |
Ruxolitinib, Free base |
|||
| 2139-5 | Biovision | EUR 248.4 | |
Imatinib, Free base |
|||
| 2141-100 | Biovision | EUR 176.4 | |
Imatinib, Free base |
|||
| 2141-1000 | Biovision | EUR 502.8 | |
Linsitinib, Free base |
|||
| 2294-25 | Biovision | EUR 679.2 | |
Linsitinib, Free base |
|||
| 2294-5 | Biovision | EUR 222 | |
Tipifarnib, Free base |
|||
| 2296-1 | Biovision | EUR 170.4 | |
Tipifarnib, Free base |
|||
| 2296-5 | Biovision | EUR 496.8 | |
Rucaparib (free base) |
|||
| A8893-10 | ApexBio | 10 mg | EUR 240 |
Rucaparib (free base) |
|||
| A8893-200 | ApexBio | 200 mg | EUR 1243.2 |
Rucaparib (free base) |
|||
| A8893-5 | ApexBio | 5 mg | EUR 164.4 |
Rucaparib (free base) |
|||
| A8893-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 170.4 |
Rucaparib (free base) |
|||
| A8893-50 | ApexBio | 50 mg | EUR 547.2 |
LY2835219 free base |
|||
| A3575-100 | ApexBio | 100 mg | EUR 686.4 |
LY2835219 free base |
|||
| A3575-25 | ApexBio | 25 mg | EUR 309.6 |
LY2835219 free base |
|||
| A3575-5 | ApexBio | 5 mg | EUR 170.4 |
R406 (free base) |
|||
| A5880-100 | ApexBio | 100 mg | EUR 1452 |
R406 (free base) |
|||
| A5880-25 | ApexBio | 25 mg | EUR 616.8 |
R406 (free base) |
|||
| A5880-5 | ApexBio | 5 mg | EUR 199.2 |
R406 (free base) |
|||
| A5880-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 316.8 |
R406 (free base) |
|||
| A5880-S | ApexBio | Evaluation Sample | EUR 97.2 |
THZ1 (Free base) |
|||
| 9664-25 | Biovision | EUR 1227.6 | |
THZ1 (Free base) |
|||
| 9664-5 | Biovision | EUR 352.8 | |
MCC950 (Free base) |
|||
| B1031-1 | Biovision | EUR 183.6 | |
MCC950 (Free base) |
|||
| B1031-5 | Biovision | EUR 548.4 | |
FIPI (free base) |
|||
| B2372-25 | Biovision | EUR 757.2 | |
FIPI (free base) |
|||
| B2372-5 | Biovision | EUR 235.2 | |
Terbinafine (Free base) |
|||
| B2423-250 | Biovision | EUR 248.4 | |
Terbinafine (Free base) |
|||
| B2423-50 | Biovision | EUR 144 | |
PLX5622 (free base) |
|||
| B2965-25 | Biovision | 25 mg | EUR 903.6 |
PLX5622 (free base) |
|||
| B2965-5 | Biovision | 5 mg | EUR 272.4 |
Apatinib (Free base) |
|||
| B1613-25 | Biovision | EUR 496.8 | |
Apatinib (Free base) |
|||
| B1613-5 | Biovision | EUR 170.4 | |
Carubicin (Free base) |
|||
| B1853-1 | Biovision | EUR 183.6 | |
Carubicin (Free base) |
|||
| B1853-5 | Biovision | EUR 548.4 | |
AZD4547, Free Base |
|||
| ADC-P-063 | Creative Biolabs | unit | Ask for price |
AZD8055, Free Base |
|||
| ADC-P-064 | Creative Biolabs | unit | Ask for price |
Cyclopamine, Free Base |
|||
| ADC-P-079 | Creative Biolabs | unit | Ask for price |
Ixabepilone, Free Base |
|||
| ADC-P-104 | Creative Biolabs | unit | Ask for price |
R406(free base) |
|||
| E1KS1533 | EnoGene | 2mg | EUR 625.2 |
Ripasudil free base |
|||
| HY-15685A | MedChemExpress | 10mg | EUR 489.6 |
Vatalanib (free base) |
|||
| HY-10203 | MedChemExpress | 5mg | EUR 142.8 |
RPR107393 free base |
|||
| HY-100299 | MedChemExpress | 1mg | EUR 577.2 |
FR167344 free base |
|||
| HY-100301 | MedChemExpress | 1mg | EUR 3164.4 |
FR183998 free base |
|||
| HY-100302 | MedChemExpress | 1mg | EUR 1352.4 |
FR194738 free base |
|||
| HY-100303 | MedChemExpress | 1mg | EUR 2388 |
YM158 (free base) |
|||
| HY-U00355 | MedChemExpress | 1mg | EUR 2770.8 |
Masupirdine (free base) |
|||
| HY-109118 | MedChemExpress | 1mg | EUR 267.6 |
R406 (free base) |
|||
| HY-11108 | MedChemExpress | 10mM/1mL | EUR 277.2 |
ITI214 (free base) |
|||
| HY-12501 | MedChemExpress | 100mg | EUR 3531.6 |
AS2863619 (free base) |
|||
| HY-126675 | MedChemExpress | 5mg | EUR 1410 |
AZD3839 (free base) |
|||
| HY-13438 | MedChemExpress | 50mg | EUR 1216.8 |
TMB free base |
|||
| TB0954 | Bio Basic | 1g | EUR 85.06 |
Xylazine (free base) |
|||
| Q-1445.0025 | Bachem | 25.0g | EUR 385.2 |
Idelalisib |
|||
| I044-100MG | TOKU-E | 100mg | EUR 142.8 |
Idelalisib |
|||
| I044-25MG | TOKU-E | 25mg | EUR 78 |
Idelalisib |
|||
| HY-13026 | MedChemExpress | 25mg | EUR 170.4 |
RGB-286638, free base |
|||
| 2886-25 | Biovision | EUR 907.2 | |
RGB-286638, free base |
|||
| 2886-5 | Biovision | EUR 274.8 | |
GSK-J4 (Free base) |
|||
| 2762-1 | Biovision | EUR 144 | |
GSK-J4 (Free base) |
|||
| 2762-5 | Biovision | EUR 314.4 | |
StemRegenin 1, Free base |
|||
| 2642-1 | Biovision | EUR 157.2 | |
StemRegenin 1, Free base |
|||
| 2642-5 | Biovision | EUR 398.4 | |
AM-095 free base |
|||
| A3167-10 | ApexBio | 10 mg | EUR 254.4 |
AM-095 free base |
|||
| A3167-100 | ApexBio | 100 mg | EUR 964.8 |
AM-095 free base |
|||
| A3167-200 | ApexBio | 200 mg | EUR 1382.4 |
AM-095 free base |
|||
| A3167-5 | ApexBio | 5 mg | EUR 199.2 |
AM-095 free base |
|||
| A3167-50 | ApexBio | 50 mg | EUR 686.4 |
SGI-1776 free base |
|||
| A4192-10 | ApexBio | 10 mg | EUR 296.4 |
SGI-1776 free base |
|||
| A4192-5 | ApexBio | 5 mg | EUR 184.8 |
SGI-1776 free base |
|||
| A4192-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 199.2 |
SGI-1776 free base |
|||
| A4192-50 | ApexBio | 50 mg | EUR 630 |
SGI-1776 free base |
|||
| A4192-S | ApexBio | Evaluation Sample | EUR 97.2 |
L-Arginine free base |
|||
| AB0205 | Bio Basic | 100g | EUR 75.78 |
-
Moreover, the epithelial injury didn’t correlate with the measured CoF of the low friction catheters, suggesting a extra nuanced pathogenesis of urethral irritation and forgeding doubt on the translatability of a solely mechanical evaluation of lubricity of urinary catheters to a scientific impact.Key phrases: Coefficient of friction; Epithelium; Eyelet; Intermittent urinary catheter; Lubricity; Urethra mannequin.
