Chemical nano-gardens: progress of salt nanowires from supramolecular self-assembly gels.
- On this article, we study the phenomenon of single-crystal halide salt wire progress at the floor of porous supplies. We report the usage of a single-step casting method with a supramolecular self-assembly gel matrix that upon drying results in the expansion of single-crystal halide (e.g., NaCl, KCl, and KI) nanowires with diameters ~130-200 nm.
CARUBICIN (FREE BASE) | TERBINAFINE (FREE BASE)
- We display their formation utilizing electron microscopy and electron-dispersive X-ray spectroscopy, exhibiting that the supramolecular gel stabilizes the expansion of those wires by facilitating a diffusion-driven base progress mechanism.
- Critically, we present that commonplace non-supramolecular gels are unable to facilitate nanowire progress. We additional present that these nanowires may be grown by seeding, forming nanocrystal gardens. This research helps perceive the potential prefunctionalization of membranes to stimulate ion-specific filters or salt efflorescence suppressors, whereas additionally offering a novel route to nanomaterial progress.
- Aloe vera has been acknowledged as a invaluable medicinal plant for the therapy of burns. In depth research have described its antiinflammatory, wound therapeutic and associated actions, however the instability of aloe gel confuses pharmacological knowledge, results in inconsistency in therapies and inconvenience in every day preparation.
IXABEPILONE, FREE BASE | GEL CASTING BASE 20 CM
- These obstacles prompted us to develop a stable aloe preparation, aloe cream, that we examined on synthetic thermal burns in mice. Aloe cream when utilized instantly to first diploma burns delayed progressive injury and accelerated the healing charge extra successfully than contemporary aloe gel. Each aloe cream and contemporary aloe gel prevented additional pores and skin injury and casting of lifeless dermis was lower than in management.
- For second diploma burns the therapeutic charge was enhanced by aloe cream and contemporary aloe gel: much less irritation was noticed in areas handled with both of those than in untreated areas or these handled with the cream base. For third diploma burns the efficacy of aloe cream and contemporary aloe gel couldn’t be evaluated statistically due to an infection.
- It was noticed that aloe cream enhanced epithelialization however failed to point out antiinflammatory activity. No variations in epithelialization and irritation had been noticed amongst mice handled with contemporary aloe gel, cream base or management. All these findings verify that Aloe vera gel is efficient for burn therapy whether it is properly preserved.
 Epothilone B |
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| 2012-1 | Biovision | EUR 137 | |
Epothilone B |
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| 2012-5 | Biovision | EUR 387 | |
Epothilone B |
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| E047-0.1MG | TOKU-E | 0.1 mg | EUR 318 |
Epothilone B |
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| E047-0.5MG | TOKU-E | 0.5 mg | EUR 1040 |
Epothilone B |
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| 20-abx076606 | Abbexa |
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|
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Epothilone B |
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| E1KS1364 | EnoGene | 5mg | EUR 521 |
Epothilone B |
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| ADC-P-087 | Creative Biolabs | unit | Ask for price |
Epothilone B |
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| HY-17029 | MedChemExpress | 10mM/1mL | EUR 158 |
 gel casting base 10 cm |
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| EVS1100-BASE | Consort | ea | EUR 150 |
 gel casting base 20 cm |
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| EVS1300-BASE | Consort | ea | EUR 200 |
 gel casting base for evs3100 |
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| EVS3100-BASE | Consort | ea | EUR 301 |
 gel casting base for evs3200 |
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| EVS3200-BASE | Consort | ea | EUR 301 |
 gel casting base for evs3300 |
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| EVS3300-BASE | Consort | ea | EUR 301 |
 Vatalanib, Free Base |
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| 2026-25 | Biovision | EUR 305 | |
Vatalanib, Free Base |
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| 2026-5 | Biovision | EUR 126 | |
 Erlotinib, Free Base |
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| 2048-100 | Biovision | EUR 158 | |
Erlotinib, Free Base |
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| 2048-1000 | Biovision | EUR 387 | |
 Linsitinib, Free base |
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| 2294-25 | Biovision | EUR 566 | |
Linsitinib, Free base |
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| 2294-5 | Biovision | EUR 185 | |
 Tipifarnib, Free base |
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| 2296-1 | Biovision | EUR 142 | |
Tipifarnib, Free base |
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| 2296-5 | Biovision | EUR 414 | |
 Sunitinib, Free base |
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| 2097-100 | Biovision | EUR 191 | |
Sunitinib, Free base |
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| 2097-1000 | Biovision | EUR 501 | |
Sunitinib, Free base |
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| 2097-25 | Biovision | EUR 115 | |
 Lapatinib, Free base |
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| 2138-100 | Biovision | EUR 387 | |
Lapatinib, Free base |
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| 2138-25 | Biovision | EUR 191 | |
 Ruxolitinib, Free base |
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| 2139-100 | Biovision | Ask for price | |
Ruxolitinib, Free base |
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| 2139-25 | Biovision | EUR 533 | |
Ruxolitinib, Free base |
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| 2139-5 | Biovision | EUR 207 | |
 Imatinib, Free base |
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| 2141-100 | Biovision | EUR 147 | |
Imatinib, Free base |
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| 2141-1000 | Biovision | EUR 419 | |
) Apatinib (Free base) |
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| B1613-25 | Biovision | EUR 414 | |
Apatinib (Free base) |
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| B1613-5 | Biovision | EUR 142 | |
) Carubicin (Free base) |
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| B1853-1 | Biovision | EUR 153 | |
Carubicin (Free base) |
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| B1853-5 | Biovision | EUR 457 | |
) FIPI (free base) |
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| B2372-25 | Biovision | EUR 631 | |
FIPI (free base) |
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| B2372-5 | Biovision | EUR 196 | |
) Terbinafine (Free base) |
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| B2423-250 | Biovision | EUR 207 | |
Terbinafine (Free base) |
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| B2423-50 | Biovision | EUR 120 | |
) MCC950 (Free base) |
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| B1031-1 | Biovision | EUR 153 | |
MCC950 (Free base) |
|||
| B1031-5 | Biovision | EUR 457 | |
) THZ1 (Free base) |
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| 9664-25 | Biovision | EUR 1023 | |
THZ1 (Free base) |
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| 9664-5 | Biovision | EUR 294 | |
) R406(free base) |
|||
| E1KS1533 | EnoGene | 2mg | EUR 521 |
 AZD4547, Free Base |
|||
| ADC-P-063 | Creative Biolabs | unit | Ask for price |
 AZD8055, Free Base |
|||
| ADC-P-064 | Creative Biolabs | unit | Ask for price |
 Cyclopamine, Free Base |
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| ADC-P-079 | Creative Biolabs | unit | Ask for price |
 Ixabepilone, Free Base |
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| ADC-P-104 | Creative Biolabs | unit | Ask for price |
) R406 (free base) |
|||
| A5880-100 | ApexBio | 100 mg | EUR 1210 |
R406 (free base) |
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| A5880-25 | ApexBio | 25 mg | EUR 514 |
R406 (free base) |
|||
| A5880-5 | ApexBio | 5 mg | EUR 166 |
R406 (free base) |
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| A5880-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 264 |
R406 (free base) |
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| A5880-S | ApexBio | Evaluation Sample | EUR 81 |
) Rucaparib (free base) |
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| A8893-10 | ApexBio | 10 mg | EUR 200 |
Rucaparib (free base) |
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| A8893-200 | ApexBio | 200 mg | EUR 1036 |
Rucaparib (free base) |
|||
| A8893-5 | ApexBio | 5 mg | EUR 137 |
Rucaparib (free base) |
|||
| A8893-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 142 |
Rucaparib (free base) |
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| A8893-50 | ApexBio | 50 mg | EUR 456 |
 LY2835219 free base |
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| A3575-100 | ApexBio | 100 mg | EUR 572 |
LY2835219 free base |
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| A3575-25 | ApexBio | 25 mg | EUR 258 |
LY2835219 free base |
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| A3575-5 | ApexBio | 5 mg | EUR 142 |
 RPR107393 free base |
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| HY-100299 | MedChemExpress | 1mg | EUR 481 |
 FR167344 free base |
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| HY-100301 | MedChemExpress | 1mg | EUR 2637 |
 FR183998 free base |
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| HY-100302 | MedChemExpress | 1mg | EUR 1127 |
 FR194738 free base |
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| HY-100303 | MedChemExpress | 1mg | EUR 1990 |
) ITI214 (free base) |
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| HY-12501 | MedChemExpress | 100mg | EUR 2943 |
) AS2863619 (free base) |
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| HY-126675 | MedChemExpress | 5mg | EUR 1175 |
) AZD3839 (free base) |
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| HY-13438 | MedChemExpress | 50mg | EUR 1014 |
 Ripasudil free base |
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| HY-15685A | MedChemExpress | 10mg | EUR 408 |
) Vatalanib (free base) |
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| HY-10203 | MedChemExpress | 5mg | EUR 119 |
) Masupirdine (free base) |
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| HY-109118 | MedChemExpress | 1mg | EUR 223 |
R406 (free base) |
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| HY-11108 | MedChemExpress | 10mM/1mL | EUR 231 |
) YM158 (free base) |
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| HY-U00355 | MedChemExpress | 1mg | EUR 2309 |
) Xylazine (free base) |
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| Q-1445.0025 | Bachem | 25.0g | EUR 321 |
) PLX5622 (free base) |
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| B2965-25 | Biovision | 25 mg | EUR 753 |
PLX5622 (free base) |
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| B2965-5 | Biovision | 5 mg | EUR 227 |
 TMB free base |
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| TB0954 | Bio Basic | 1g | EUR 70.88 |
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A Biomimetic Urethral Mannequin to Consider Urinary Catheter Lubricity and Epithelial Micro-Trauma
-
The usual technique of evaluating the lubricity of intermittent urinary catheters with coefficient of friction (CoF) testing shouldn’t be physiologically related, whereas there’s additionally a dearth of printed analysis on catheter-associated urethral micro-trauma. We developed a novel human urethral epithelial cell-seeded mannequin of the urethra to switch the rubber counter-surface utilized in commonplace CoF testing.
ERLOTINIB, FREE BASE | MCC950 (FREE BASE)
-
This cell-seeded mannequin, at the side of a novel testing system, permits an investigation of catheter-associated epithelial micro-trauma in vitro for the primary time. The CoF of 4 manufacturers of commercially-available hydrophilic-coated intermittent catheters was measured utilizing each the rubber and urethral mannequin counter-surfaces.bodel, the injury to the epithelial layer was analysed utilizing commonplace cell imaging.
-
The rubber counter-surface was proven to over-estimate the CoF of gel-coated catheters in comparison with our urethral mannequin because of stick-slip behaviour attributable to polymer-on-polymer interplay of the catheter base material on the rubber counter-surface. We recognized no deleterious impact as a result of presence or design of catheter eyelets to both the CoF measurements or the diploma of epithelium injury in our mannequin.
gel casting base 10 cm |
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| EVS1100-BASE | Consort | ea | EUR 150 |
gel casting base 20 cm |
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| EVS1300-BASE | Consort | ea | EUR 200 |
gel casting base for evs3100 |
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| EVS3100-BASE | Consort | ea | EUR 301 |
gel casting base for evs3200 |
|||
| EVS3200-BASE | Consort | ea | EUR 301 |
gel casting base for evs3300 |
|||
| EVS3300-BASE | Consort | ea | EUR 301 |
Vatalanib, Free Base |
|||
| 2026-25 | Biovision | EUR 305 | |
Vatalanib, Free Base |
|||
| 2026-5 | Biovision | EUR 126 | |
Erlotinib, Free Base |
|||
| 2048-100 | Biovision | EUR 158 | |
Erlotinib, Free Base |
|||
| 2048-1000 | Biovision | EUR 387 | |
Linsitinib, Free base |
|||
| 2294-25 | Biovision | EUR 566 | |
Linsitinib, Free base |
|||
| 2294-5 | Biovision | EUR 185 | |
Tipifarnib, Free base |
|||
| 2296-1 | Biovision | EUR 142 | |
Tipifarnib, Free base |
|||
| 2296-5 | Biovision | EUR 414 | |
Sunitinib, Free base |
|||
| 2097-100 | Biovision | EUR 191 | |
Sunitinib, Free base |
|||
| 2097-1000 | Biovision | EUR 501 | |
Sunitinib, Free base |
|||
| 2097-25 | Biovision | EUR 115 | |
Lapatinib, Free base |
|||
| 2138-100 | Biovision | EUR 387 | |
Lapatinib, Free base |
|||
| 2138-25 | Biovision | EUR 191 | |
Ruxolitinib, Free base |
|||
| 2139-100 | Biovision | Ask for price | |
Ruxolitinib, Free base |
|||
| 2139-25 | Biovision | EUR 533 | |
Ruxolitinib, Free base |
|||
| 2139-5 | Biovision | EUR 207 | |
Imatinib, Free base |
|||
| 2141-100 | Biovision | EUR 147 | |
Imatinib, Free base |
|||
| 2141-1000 | Biovision | EUR 419 | |
Apatinib (Free base) |
|||
| B1613-25 | Biovision | EUR 414 | |
Apatinib (Free base) |
|||
| B1613-5 | Biovision | EUR 142 | |
Carubicin (Free base) |
|||
| B1853-1 | Biovision | EUR 153 | |
Carubicin (Free base) |
|||
| B1853-5 | Biovision | EUR 457 | |
FIPI (free base) |
|||
| B2372-25 | Biovision | EUR 631 | |
FIPI (free base) |
|||
| B2372-5 | Biovision | EUR 196 | |
Terbinafine (Free base) |
|||
| B2423-250 | Biovision | EUR 207 | |
Terbinafine (Free base) |
|||
| B2423-50 | Biovision | EUR 120 | |
MCC950 (Free base) |
|||
| B1031-1 | Biovision | EUR 153 | |
MCC950 (Free base) |
|||
| B1031-5 | Biovision | EUR 457 | |
THZ1 (Free base) |
|||
| 9664-25 | Biovision | EUR 1023 | |
THZ1 (Free base) |
|||
| 9664-5 | Biovision | EUR 294 | |
R406(free base) |
|||
| E1KS1533 | EnoGene | 2mg | EUR 521 |
AZD4547, Free Base |
|||
| ADC-P-063 | Creative Biolabs | unit | Ask for price |
AZD8055, Free Base |
|||
| ADC-P-064 | Creative Biolabs | unit | Ask for price |
Cyclopamine, Free Base |
|||
| ADC-P-079 | Creative Biolabs | unit | Ask for price |
Ixabepilone, Free Base |
|||
| ADC-P-104 | Creative Biolabs | unit | Ask for price |
R406 (free base) |
|||
| A5880-100 | ApexBio | 100 mg | EUR 1210 |
R406 (free base) |
|||
| A5880-25 | ApexBio | 25 mg | EUR 514 |
R406 (free base) |
|||
| A5880-5 | ApexBio | 5 mg | EUR 166 |
R406 (free base) |
|||
| A5880-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 264 |
R406 (free base) |
|||
| A5880-S | ApexBio | Evaluation Sample | EUR 81 |
Rucaparib (free base) |
|||
| A8893-10 | ApexBio | 10 mg | EUR 200 |
Rucaparib (free base) |
|||
| A8893-200 | ApexBio | 200 mg | EUR 1036 |
Rucaparib (free base) |
|||
| A8893-5 | ApexBio | 5 mg | EUR 137 |
Rucaparib (free base) |
|||
| A8893-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 142 |
Rucaparib (free base) |
|||
| A8893-50 | ApexBio | 50 mg | EUR 456 |
LY2835219 free base |
|||
| A3575-100 | ApexBio | 100 mg | EUR 572 |
LY2835219 free base |
|||
| A3575-25 | ApexBio | 25 mg | EUR 258 |
LY2835219 free base |
|||
| A3575-5 | ApexBio | 5 mg | EUR 142 |
RPR107393 free base |
|||
| HY-100299 | MedChemExpress | 1mg | EUR 481 |
FR167344 free base |
|||
| HY-100301 | MedChemExpress | 1mg | EUR 2637 |
FR183998 free base |
|||
| HY-100302 | MedChemExpress | 1mg | EUR 1127 |
FR194738 free base |
|||
| HY-100303 | MedChemExpress | 1mg | EUR 1990 |
ITI214 (free base) |
|||
| HY-12501 | MedChemExpress | 100mg | EUR 2943 |
AS2863619 (free base) |
|||
| HY-126675 | MedChemExpress | 5mg | EUR 1175 |
AZD3839 (free base) |
|||
| HY-13438 | MedChemExpress | 50mg | EUR 1014 |
Ripasudil free base |
|||
| HY-15685A | MedChemExpress | 10mg | EUR 408 |
Vatalanib (free base) |
|||
| HY-10203 | MedChemExpress | 5mg | EUR 119 |
Masupirdine (free base) |
|||
| HY-109118 | MedChemExpress | 1mg | EUR 223 |
R406 (free base) |
|||
| HY-11108 | MedChemExpress | 10mM/1mL | EUR 231 |
YM158 (free base) |
|||
| HY-U00355 | MedChemExpress | 1mg | EUR 2309 |
Xylazine (free base) |
|||
| Q-1445.0025 | Bachem | 25.0g | EUR 321 |
PLX5622 (free base) |
|||
| B2965-25 | Biovision | 25 mg | EUR 753 |
PLX5622 (free base) |
|||
| B2965-5 | Biovision | 5 mg | EUR 227 |
TMB free base |
|||
| TB0954 | Bio Basic | 1g | EUR 70.88 |
|
|||
 Idelalisib |
|||
| HY-13026 | MedChemExpress | 25mg | EUR 142 |
Idelalisib |
|||
| I044-100MG | TOKU-E | 100mg | EUR 119 |
Idelalisib |
|||
| I044-25MG | TOKU-E | 25mg | EUR 65 |
 RGB-286638, free base |
|||
| 2886-25 | Biovision | EUR 756 | |
RGB-286638, free base |
|||
| 2886-5 | Biovision | EUR 229 | |
 StemRegenin 1, Free base |
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| 2642-1 | Biovision | EUR 131 | |
StemRegenin 1, Free base |
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| 2642-5 | Biovision | EUR 332 | |
) GSK-J4 (Free base) |
|||
| 2762-1 | Biovision | EUR 120 | |
GSK-J4 (Free base) |
|||
| 2762-5 | Biovision | EUR 262 | |
) BMS-345541 (Free base) |
|||
| B1907-1 | Biovision | EUR 142 | |
BMS-345541 (Free base) |
|||
| B1907-5 | Biovision | EUR 414 | |
 UNC-926, free base |
|||
| B2158-25 | Biovision | EUR 631 | |
UNC-926, free base |
|||
| B2158-5 | Biovision | EUR 196 | |
 SB-334867 free base |
|||
| B3423-100 | ApexBio | 100 mg | EUR 599 |
SB-334867 free base |
|||
| B3423-25 | ApexBio | 25 mg | EUR 290 |
SB-334867 free base |
|||
| B3423-5 | ApexBio | 5 mg | EUR 128 |
SB-334867 free base |
|||
| B3423-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 131 |
) BMS-345541(free base) |
|||
| B4655-10 | ApexBio | 10 mg | EUR 235 |
BMS-345541(free base) |
|||
| B4655-5 | ApexBio | 5 mg | EUR 171 |
BMS-345541(free base) |
|||
| B4655-50 | ApexBio | 50 mg | EUR 595 |
 GSK J4 free base |
|||
| B5959-10 | ApexBio | 10 mg | EUR 373 |
-
Moreover, the epithelial injury didn’t correlate with the measured CoF of the low friction catheters, suggesting a extra nuanced pathogenesis of urethral irritation and forgeding doubt on the translatability of a solely mechanical evaluation of lubricity of urinary catheters to a scientific impact.Key phrases: Coefficient of friction; Epithelium; Eyelet; Intermittent urinary catheter; Lubricity; Urethra mannequin.
